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In addition to motor tests, cognition was assessed using the Mattis Dementia Rating Scale 2, a test battery to analyze cognitive impairments in patients with PD [179]

Their combined action also helps optimize body composition by reducing fat and enhancing overall physical performance, making them a dynamic choice for fitness and recovery goals

From a translational perspective, this raises the possibility that combined modulation of these pathways could stabilize the neurovascular unit and preserve cerebral homeostasis

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